Reviews for triftazin. The drug "Triftazin": instructions for use, price, analogues, reviews. Overdose, side effects and cancellation of "Triftazin" Triftazin side effects

Weakens the effects of levodopa and phenamine derivatives, the latter reduce the antipsychotic activity of trifluoperazine. Enhances the effect of ethanol and other drugs that depress the central nervous system (general anesthesia, narcotic analgesics, opioids, barbiturates), as well as atropine.

When taken simultaneously with antiepileptic drugs (including barbiturates), it reduces their effect (reduces the epileptic threshold).

Reduces the effect of anorexigenic drugs (with the exception of fenfluramine).

Reduces the effectiveness of the emetic action of apomorphine, enhances its inhibitory effect on the central nervous system.

Increases plasma concentration of prolactin and interferes with the action of bromocriptine. When combined with tricyclic antidepressants, maprotiline, monoamine oxidase inhibitors, it is possible to lengthen and enhance the sedative and anticholinergic effects, with thiazide diuretics - the occurrence of electrolyte imbalance, with lithium preparations - a decrease in absorption in the gastrointestinal tract, an increase in the rate of lithium excretion by the kidneys, an increase in the severity extrapyramidal disorders, early signs of lithium intoxication (nausea and vomiting) may be masked by the antiemetic effect of trifluoperazine.

When combined with beta-blockers, it enhances the hypotensive effect, increases the risk of developing irreversible retinopathy, arrhythmias and tardive dyskinesia. Reduces the effect of indirect anticoagulants.

Antithyroid drugs increase the risk of developing agranulocytosis. Probucol, cisapride, disopyramide, pimozide, contribute to an additional lengthening of the QT interval, which increases the risk of developing ventricular tachycardia.

With the simultaneous use of phenothiazides with propranolol, an increase in the concentration of both drugs is noted.

For the correction of extrapyramidal disorders, antiparkinsonian drugs are used - and others; dyskinesias are stopped subcutaneously with the introduction of 2 ml of a 20% caffeine solution and 1 ml of a 0.1% atropine solution).

The drug, having a cardiotoxic effect, can cause arterial hypotension, deterioration of cardiac hemodynamics (pulmonary edema, ventricular fibrillation and, as a result of the latter, sudden death) in elderly patients with psychoses.

Elderly patients may develop irreversible dyskinesias. If signs of tardive dyskinesia, neuroleptic malignant syndrome appear, treatment should be discontinued.

During therapy with phenothiazines, it is possible to obtain false-positive tests for phenylketonuria.

The appointment of phenothiazines should be discontinued at least 48 hours before the proposed myelography (resumption is possible after 24 hours).

Coated tablets, 5 mg or 10 mg.

10 coated tablets in a blister pack made of polyvinyl chloride film and printed lacquered aluminum foil.

50 or 100 coated tablets in a glass jar, corked with a plastic lid or in a polymer jar.

Antipsychotic agent (neuroleptic), piperazine derivative of phenothiazine. It is believed that the antipsychotic effect of phenothiazines is due to the blocking of postsynaptic mesolimbic dopaminergic receptors in the brain. The intensity of antipsychotic action surpasses chlorpromazine. It has a strong antiemetic effect, the central mechanism of which is associated with inhibition or blockade of dopamine D 2 receptors in the chemoreceptor trigger zone of the cerebellum, and the peripheral mechanism is associated with blockade of the vagus nerve in the gastrointestinal tract. It has alpha-adrenergic blocking activity. It has some activating effect. Anticholinergic activity and hypotensive effect are weakly expressed. It has a pronounced extrapyramidal effect. Unlike chlorpromazine, it does not have antihistamine, antispasmodic and anticonvulsant effects.

Pharmacokinetics

Clinical data on the pharmacokinetics of trifluoperazine are limited.

Phenothiazines have high plasma protein binding. Excreted mainly by the kidneys and partly with bile.

Release form

10 pieces. - cellular contour packings (5) - packs of cardboard.
100 pieces. - jars of dark glass (1) - packs of cardboard.
50 pcs. - jars of dark glass (1) - packs of cardboard.
100 pieces. - polymer cans (1) - packs of cardboard.
50 pcs. - polymer cans (1) - packs of cardboard.
50 pcs. - glass jars (1) - cardboard packs.

Dosage

Individual. Inside adults - 1-5 mg 2 times / day; if necessary, within 2-3 weeks, the dose is increased to 15-20 mg / day, the frequency of use is 3 times / day. Children aged 6 years and older - 1 mg 2-3 times / day, if necessary, the dose can be increased to 5-6 mg / day.

In / m adults - 1-2 mg every 4-6 hours. Children - 1 mg 1-2 times / day.

Maximum doses: adults when taken orally - 40 mg / day, / m - 10 mg / day.

Interaction

With the simultaneous use of drugs that have a depressant effect on the central nervous system, ethanol, ethanol-containing drugs, it is possible to increase the inhibitory effect on the central nervous system and respiratory function.

With simultaneous use with anticonvulsants, a decrease in the threshold of convulsive readiness is possible; with agents that cause extrapyramidal reactions, an increase in the frequency and severity of extrapyramidal disorders is possible.

With simultaneous use with tricyclic antidepressants, maprotiline, MAO inhibitors, the risk of developing NMS increases.

With simultaneous use with drugs that cause arterial hypotension, severe orthostatic hypotension is possible.

With simultaneous use with drugs for the treatment of hyperthyroidism, the risk of developing agranulocytosis increases.

With simultaneous use with anticholinergic drugs, their anticholinergic effects are enhanced, while the antipsychotic effect of the neuroleptic may decrease.

With the simultaneous use of antacids, antiparkinsonian drugs, the absorption of phenothiazines is impaired.

With simultaneous use, the effect of oral anticoagulants is weakened, the effectiveness of amphetamines, levodopa, clonidine, guanethidine, epinephrine, ephedrine may decrease.

With simultaneous use with lithium salts, a neurotoxic effect, the development of extrapyramidal symptoms are possible.

With simultaneous use with methyldopa, a case of the development of paradoxical arterial hypertension has been described.

With simultaneous use with fluoxetine, extrapyramidal symptoms and dystonia may develop.

Side effects

From the side of the central nervous system: drowsiness, dizziness, dry mouth, sleep disorders, fatigue, visual disturbances; extrapyramidal disorders, tardive dyskinesia.

From the digestive system: anorexia, cholestatic jaundice.

From the hemopoietic system: thrombocytopenia, anemia, agranulocytopenia, pancytopenia.

From the side of the cardiovascular system: tachycardia, moderate orthostatic hypotension, cardiac arrhythmias, ECG changes (prolongation of the QT interval, smoothing of the T wave).

Allergic reactions: skin rash, urticaria, angioedema.

From the endocrine system: galactorrhea, amenorrhea.

Indications

Psychotic disorders, incl. schizophrenia. Psychomotor agitation. Neurosis with a predominance of anxiety and fear. Symptomatic treatment of nausea and vomiting.

Contraindications

Coma states; diseases accompanied by myelodepression; severe liver dysfunction; pregnancy, lactation; hypersensitivity to trifluoperazine.

Application features

Use during pregnancy and lactation

Trifluoperazine is contraindicated for use during pregnancy and lactation.

Experimental studies have shown that trifluoperazine (in doses significantly higher than clinical doses) can increase the incidence of malformations and reduce the body weight of newborn animals.

Phenothiazines pass into breast milk and can cause drowsiness and increase the risk of tardive dyskinesia in a child.

Application for violations of liver function

Use in children

Use in elderly patients

special instructions

Should not be used in depression.

With extreme caution used in patients with glaucoma, with cardiovascular disease, epilepsy, benign prostatic hyperplasia; with hypersensitivity to other drugs of the phenothiazine series. Phenothiazines are used after comparing the risks and benefits of treatment in patients with pathological changes in the blood picture, with impaired liver function, alcohol intoxication, Reye's syndrome, as well as with breast cancer, Parkinson's disease, gastric and duodenal ulcers, urinary retention, chronic organ diseases breathing (especially in children), epileptic seizures, vomiting.

The simultaneous use of phenothiazines with adsorbent antidiarrheal agents should be avoided.

Elderly patients require correction of the dosing regimen of trifluoperazine. During the period of treatment, alcohol should be excluded.

Influence on the ability to drive vehicles and control mechanisms

It should be used with caution in patients whose activities require an increased concentration of attention and a high speed of psychomotor reactions.

Result: negative feedback

11 +

An ancient medicine that does more harm than good

Pros: Cheap, pacifies

Cons: Severe side effects

An ancient drug, hence not only the low price, but also the strongest side effects. Yes, Triftazin is effective - it calms and pacifies even with acute psychosis, but it also makes you a weak-willed vegetable: muscles turn into jelly, legs don’t hold, you can’t chew normally, drooling, and your head is terribly spinning and doesn’t think, it doesn’t even work navigate in space. It "weathers" only after 1-2 days, so stay away from it.

Result: negative feedback

Benefits: no

Cons: Some cons, many side effects

Result: negative feedback

Dangerous antipsychotic

Benefits: No.

Cons: Lots of side effects that are impossible to get rid of.

You wouldn't wish on your enemy the health problems that appear as side effects when taking Triftazin. It was prescribed to me by doctors as an antipsychotic for anxiety disorders. I didn’t see much benefit from it, but I can list what I felt: insomnia, complete loss of sexual desire, constant anxiety, inability to focus on something specific, etc. I, as an obedient patient, having felt the first disturbing side effects, did not quit this drug. This was my mistake. When my condition became completely unstable, and I turned into an unbalanced person, I decided to stop taking it. Contrary to my expectations about the normalization of the state, the consequences were irreversible. All symptoms remained after the end of treatment.

Result: positive feedback

Reliable, proven, but with side effects

Advantages: Low price, effect

Disadvantages: The tablet is small, it is inconvenient to divide in half.

I take Triftazin 0.25 mg in the morning and evening. My diagnosis is f20, the doctor likes to prescribe it, like vitamins, the drug is proven and has proven itself well. If I do not exceed the dosage, then there are usually no side effects, if I start to get carried away and go beyond the limits prescribed by the doctor, then spasms begin: the muscles of the face warp, the larynx is tense, the mouth is dry, the tongue sometimes sinks. When I just started taking it, I noticed that motor activity increased, I ran back and forth and repeated the same actions, it was a little annoying. Then it became easier, obsessive thoughts and mood swings were released, but apathy began.

Result: negative feedback

Unsafe agent

Benefits: Works as a sleeping pill, relieves mania, pacifies the disease, inexpensive

Cons: Highly harmful, addictive

They prescribed it to me a long time ago, then it seemed to help. She stopped freaking out, she slept like a dead woman, the mania disappeared. But the consequences of this treatment had to be disentangled for a long time. Triftazin terribly hurts the liver - mine lost all positions after less than a month, swelled up to terrible sizes, vomited 4-5 times every day, I generally keep quiet about diarrhea. All the time she drank it, she suffered from terrible nighttime cramps, and in the end, for some reason, her tongue began to go numb, one night she almost choked on it. It was full of other side effects, like frequent migraines, digestive problems, but the saddest thing is that the drug even in this month managed to make me addicted. As soon as I stopped drinking it, I completely stopped sleeping, and the disease worsened in a way that it had never worsened before, I had to go to the hospital urgently. Since then, I have stayed away from cheap pills, I’d rather spend money on expensive antipsychotics than experience this again.

Triftazin belongs to the group of neuroleptics and is antipsychotic drug.

The composition of this tool includes an active component - trifluoperazine hydrochloride (5 mg per tablet; 2 mg in 1 ml of injection), as well as excipients, depending on the form of release.

The presence of an active substance that, by blocking certain brain receptors, has a sedative, hypothermic, antiemetic, hypotensive and cataleptic effect, determines the medicinal properties of the drug.

In comparison with other drugs of similar action, Triftazin acts more actively and is better tolerated by patients.

Over the years of practice of using the drug, Triftazin has proven its effectiveness in the treatment of psychosis, nervous disorders, delirium, paranoia and hallucinations.

Pharmacokinetics

After entering the body, the active component of Triftazin "binds" to blood proteins. The maximum concentration is reached within 1-2 hours after ingestion. It is metabolized in the liver, and then excreted from the body with bile and urine.

Please note that this drug can pass into breast milk.

Indications for use

Due to the effect of the active ingredient Triftazin on the nervous system, this drug indicated for the treatment of:

• schizophrenia (sluggish, periodic; paranoid, accompanied by hallucinations, neurosis-like and other forms of this disease);
• mental disorders accompanied by delusions and hallucinations, paranoia and obsessive-compulsive states;
• neurosis (including age-related and caused by alcohol).

Also used as an antiemetic for central vomiting.

Contraindications for the use of the drug

Triftazin is contraindicated at:

• brain injuries;
• coma of the patient;
• depression of the functions of the central nervous system;
• diseases of the brain (head and spinal);
• acute peptic ulcer of the stomach and duodenum;
• some diseases of the blood and heart;
• violations of the functions of the liver and kidneys;
• closed glaucoma;
• myxedema.

In addition, the drug not intended for children under 3 years of age, as well as patients with hypersensitivity to the drug or individual intolerance to its components.

Instructions for use states that in the presence of the following diseases, Triftazin should be used carefully:

• respiratory dysfunction;
• some diseases of the heart and vascular system;
• peptic ulcer in remission;
• malignant tumors in the mammary glands;
• epilepsy;
• Parkinson's disease;
• alcohol addiction.

Mechanism of action

Once in the body, trifluoperazine has a blocking effect on some receptors in the brain. Thus, the drug exhibits its antipsychotic properties and normalize the condition of patients.

By blocking certain receptors in the cerebellum and the vagus nerve in the gastrointestinal tract, Triftazin stops vomiting.

Method of application and dosage

According to the instructions for use, Triftazin is used orally (in the form of tablets) or by intramuscular injection (in the form of a solution).

The dosage is prescribed individually, depending on the condition of the patient, his age, the desired effect and other factors.

The duration of treatment is also determined in each case, but, as a rule, does not exceed 12 weeks. The use of Triftazin should not be stopped abruptly, the dosage should be gradually reduced.

Treatment with pills

Depending on the task and the disease, there will be such dosages drug:

1. anxiety syndrome. The usual dose is 1-2 mg per day, but sometimes it can be increased to 6 mg.
2. Psychotic disorders. At the beginning of treatment, the dose of the drug is 2.5-5 mg per day and is divided into 2 doses. Gradually, the dosage increases to 15-20 mg, in rare cases up to 40 mg. The duration of treatment is 2-3 weeks.
3. Vomit. As a rule, 1-4 mg of Triftazin is prescribed per day.

Treatment by intramuscular injection

This method is used when a quick effect is needed. As a rule, they begin to administer 1-2 mg of the drug with a frequency of 6-12 hours, gradually increasing the dosage to 6-10 mg per day.

What is dangerous overdose

An overdose of Triftazin is accompanied by such symptoms: drowsiness, stupor, confusion, convulsions, cardiac arrhythmia, hypothermia, in severe cases, the patient may fall into a coma.

Help with overdose is according to the symptoms. As a rule, first you need to do a gastric lavage.

With signs of an overdose, you need to urgently go to the hospital so that the doctor determines the drugs necessary for treatment, because with various manifestations of an overdose, treatment is determined individually. If necessary, artificial ventilation of the lungs, oxygen therapy can be carried out.

Side effect

Triftazin can have a negative effect on the body and when used correctly.

Side effects of the drug on various body systems:

1. Nervous system: dizziness, insomnia at the initial stage of treatment and increased drowsiness in the future, muscle spasms, impaired coordination of movements, convulsions, non-standard reaction to external stimuli.
2. The cardiovascular system: jumps in blood pressure, heart rhythm disturbance, anemia, inhibition of bleeding in the bone marrow.
3. Digestive system: nausea, vomiting, constipation at the initial stage of treatment, diarrhea, loss of appetite, hepatitis.
4. Urogenital system: violation of the urinary system, decreased libido.
5. Endocrine system: glucosuria, gynecomastia, weight gain, breast pain.
6. Allergic reactions: skin rashes, swelling.

In addition, as a result of taking the drug, vision may deteriorate, sometimes there is a discoloration of the cornea. The patient may also become more sensitive to high temperatures.

Special instructions for use and precautions

During pregnancy, Triftazin is contraindicated, because. its active component trifluoperazine can adversely affect the development of the fetus.

Also during lactation you should stop taking this drug, because its active substance can pass into breast milk.

Carefully Triftazin should be used in the elderly, because it is likely to develop irreversible processes that cause involuntary movements (dyskinesia).
During the period of treatment with this drug, exposure to high temperatures should be avoided, because patients may have impaired thermoregulation.

It is necessary to regularly monitor blood pressure, pulse rate, and monitor the normal functioning of the kidneys and liver.

It is forbidden to drink alcohol during the period of use of this drug!

During the period of treatment with Triftazin, you should refrain from driving a car, as well as from engaging in activities that require attention and concentration, because. the drug causes drowsiness, lethargy and distraction.

Released only by prescription.

Interaction with other drugs

Triftazin interacts with many drugs, and this does not always have a positive effect on the patient's health. Therefore, before combining drugs, you should consult with doctor:

• with simultaneous use with drugs that depress the function of the central nervous system, it is possible to disrupt the activity of the central nervous system and respiratory function;
• combination with analgesics can lead to hyperthermia; with antidepressants - to the development of neuroleptic malignant syndrome;
• simultaneous use with epinephrine should be avoided, since such a combination can cause a sharp drop in blood pressure, and with prochlorperazine, since this can lead to prolonged loss of consciousness.

Terms and conditions of storage

It is necessary to store the drug in a dark place, out of the reach of children.

Shelf life - 3-4 years.

Release form and cost

Triftazin is available in two forms: a solution for intramuscular injection (clear or slightly yellowish) and yellow or blue-green coated tablets.

The price of Triftazin depends on the form release:

• tablets - 30-60 rubles;
• ampoules for injections - 35-65 rubles.

Feedback from doctors and patients

Reviews of doctors and patients about Triftazin are mostly positive, but the instructions for use must be studied before use - all the little things are important.

Patients, used Triftazin, they note that the drug is effective in the treatment of hallucinations, however, it does not always effectively cope with delusional states.

Almost all patients felt drowsiness, lethargy during treatment with this drug, some side effects affected visual acuity, speech functions, memory work. In isolated cases, patients write about weight gain while taking Triftazin.

Compared with haloperidol drugs, there is more soft action and safety Triftazina.

Many patients write that in parallel with this drug, doctors prescribe correctors that make it easier to tolerate the side effects of Triftazin and improve the general condition during the treatment period.

Doctors note that Triftazin in some cases is more effective than similar drugs in dealing with delirium, anxiety, obsessive-compulsive disorders. However, you should strictly follow the rules for using the drug, because the risk of overdose is high.

If you are concerned about any effect of the medicine or lack of visible action, you should contact a specialist who can adjust the treatment if necessary.

Advantages:

• effective for the treatment of neuroses;
• after taking, there is an improvement in sleep;
• some patients note that the drug acts as an antidepressant;
• copes well with hallucinatory states;
• milder action compared to haloperidol drugs.

Flaws Triftazina:

A significant number of contraindications, side effects;

High risk of overdose;

Most patients note drowsiness, lethargy, unwillingness to do any business during the treatment period;

The drug negatively affects the ability to concentrate;

Cases of deterioration of vision and memory in patients taking Triftazin are not uncommon.

The drug has found wide application in neurology and other interesting facts are in our article.

With age, blood circulation in the brain can be disturbed, senile dementia occurs, at the first stage they are not obvious and difficult to detect.

Drugs that can replace Triftazin

Triftazin analogues are quite numerous and have advantages and disadvantages over him.

Exazine

Pharmacological group - neuroleptics. Applicable for schizophrenia, psychosis, hallucinatory state, vomiting of central origin.

The active substance component is trifluoperazine, the concentration of which in the preparation is similar to that of Triftazin.

Contraindications, precautions and application features are similar to Triftazin. It is possible to use the drug during pregnancy if the benefit to the mother outweighs the potential risk to the fetus.

Available in the form of tablets and solution for intramuscular injection.

Stelazin

Belongs to the pharmacological group of neuroleptics, has antipsychotic properties. Dosage form: tablets and solution for intramuscular injections.

Indications for use, features of treatment and contraindications are similar to Triftazin.

Contains one active ingredient - trifluoperazine. Each tablet contains 1 mg or 5 mg of the active substance, in solution - 1 mg per 1 ml.

Trazyn

neuroleptic drug, has an antipsychotic effect.

Indications for use: similar to Triftazin.

Trifluoperazine is the active component of the drug and determines its medicinal properties. The content of the active ingredient in tablets is higher than in Triftazin (5 and 10 mg per tablet).

Contraindications and application features are similar to Triftazin. Treatment with this drug during pregnancy is possible if the benefit to the mother outweighs the potential risk to the child.

Release form: tablets; solution for intramuscular injections.

Instructions for use:

Triftazin (Triphtazinum) is an antipsychotic used for the effective treatment of mental disorders and schizophrenia.

Pharmacological action of Triftazin

The drug is an antipsychotic agent with sedative, antiemetic, anti-icotic, hypomermic, cataleptic, hypotensive and mild m-anticholinergic action. Triftazine is similar in structure to chlorpromazine, but has a higher activity and is better tolerated.

Release form

Triftazin is produced in the form of coated tablets, in cellular packages, in cardboard packs of 10 and 50 pieces, or in ampoules of 1 ml of a 0.2% solution of 10 pieces.

Triftazin's analogs

Triftazin's analogue for the active substance is Triftazin-Darnitsa. Analogues of Triftazin according to the mechanism of action and belonging to the same pharmacological group include:

• Mazheptil;
• Meterazine;
• Moditen;
• Etaperazine.

Indications for use Triftazin

The drug Triftazin is used in cases of schizophrenia, psychosis, hallucinatory and affective-delusional states, psychomotor agitation and vomiting (of central origin).

How to use Triftazin

In accordance with the instructions, Triftazin tablets are taken orally, washed down with plenty of water, or injected intramuscularly in the form of a solution. The dosage of the drug depends on age and disease. For the treatment of anxiety syndrome with Triftazin tablets, the dose is 1-2 mg twice a day, the maximum dose is 6 mg per day, for no more than 12 weeks. In the treatment of psychotic disorders, the drug is prescribed in an amount of 2.5-5 mg twice a day, orally, with an increase to 15-20 mg per day for 2-3 weeks, the maximum dose is 40 mg per day. The use of Triftazin inside in the elderly and debilitated patients begins with a lower initial dose, which, if necessary, can be increased. For children over the age of 6 years, the dosage of the drug is 1 mg 1-2 times a day with a possible gradual increase.

A single dose of the drug Triftazin when administered intramuscularly is 1-2 mg every 4-6 hours, but not more than 10 mg per day. In accordance with the instructions, Triftazin is prescribed to the elderly, as well as to debilitated and malnourished patients at the initial dose, reduced by 2 times. For children over the age of 6 years, the dosage of the drug is 1 mg 1-2 times a day.

Contraindications

According to the instructions, Triftazin is contraindicated for use in:

• Violation of the excretory function of the kidneys;
• severe liver failure;
• Inhibition of bone marrow hematopoiesis;
• Progressive diseases of the brain and spinal cord;
• Traumatic brain injuries;
• Coma states of any etiology;
• Pronounced inhibition of the function of the central nervous system;
• Severe cardiovascular diseases;
• Hypersensitivity.

The drug Triftazin, according to the instructions, is prescribed with caution for alcoholism, angina pectoris, valvular heart disease, pathological changes in the blood, breast cancer, angle-closure glaucoma, prostatic hyperplasia, liver and kidney failure, gastric ulcer and duodenal ulcer.

Triftazin is also used with caution according to the instructions for Parkinson's disease, epilepsy, myxedema, Reye's syndrome, cachexia and vomiting.

The drug Triftazin is prescribed with caution in the elderly, do not prescribe to children under the age of 3 years, pregnant women and during lactation.

Side effects of Triftazin

The use of Triftazin according to reviews can lead to complications from various body systems in cases of overdose, namely:

• Nervous system: insomnia, dizziness, drowsiness, akathisia, parkinsonism, tardive dyskinesia, dystonic extrapyramidal reactions, neuroleptic malignant syndrome, mental indifference phenomena, mental changes and delayed reaction to external stimuli;
• Endocrine system: hypoglycemia, glucosuria, hyperprolactinemia, galactorrhea, pain or swelling in the mammary glands, amenorrhea, hyperglycemia, dysmenorrhea and weight gain;
• Genitourinary system: oliguria, decreased potency, priapism, frigidity, decreased libido, impaired ejaculation and urinary retention;
• Digestive system: nausea, loss of appetite, dryness of the oral mucosa, constipation, gastralgia, bulimia, anorexia, vomiting, diarrhea, cholestatic jaundice, hepatitis and intestinal paresis;
• Hematopoietic organs: leukopenia, thrombocytopenia, pancytopenia, agranulocytosis, eosinophilia and hemolytic anemia;
• Sense organs: visual impairment (paresis of accommodation), clouding of the lens and cornea, retinopathy and blurred vision;
• Cardiovascular system: decrease or inversion of the T wave, prolongation of the Q-T interval, cardiac arrhythmia and increased frequency of angina attacks.

In addition, Triftazin, according to reviews, can cause other disorders, namely:

• skin rash;
• Angioedema;
• Urticaria;
• exfoliative dermatitis;
• conjunctiva;
• Skin coloring;
• photosensitivity;
• discoloration of the sclera and cornea;
• myasthenia gravis;
• Phenylketonuria.

Also, the use of Triftazin according to reviews can lead to the development of heat stroke, loss of the ability to sweat, confusion and false positive pregnancy tests.

An overdose of the drug can lead to neuroleptic malignant syndrome, lowering blood pressure, hypothermia, tachycardia, gynecomastia, coma, collapse and toxic hepatitis.

Storage conditions

In accordance with the instructions, Triftazin must be stored out of the reach of children and protected from light, in a dry place, at room temperature up to 25 ° C. The shelf life, subject to the recommendations, is 4 years.